NAD+ 500MG
55,00 $
NAD+ (Nicotinamide Adenine Dinucleotide) Research Compound – Cellular Energy & Longevity
Product Overview:
NAD+ (Nicotinamide Adenine Dinucleotide) is a crucial coenzyme found in all living cells, playing a fundamental role in energy metabolism, DNA repair, and cellular signaling. This oxidized form of NAD is essential for the function of sirtuins, PARPs, and other enzymes critical for longevity and cellular health. Our NAD+ is synthesized for advanced biochemical and aging research with pharmaceutical-grade purity.
Key Features:
- High Purity: ≥99% purity verified by independent HPLC analysis
- Available Concentrations: 500mg lyophilized powder vials
- Research Grade: Manufactured in ISO-certified facility under strict quality control
- Stable Formulation: Lyophilized powder ensures maximum potency and extended shelf life
- Biologically Active: Oxidized form (NAD⁺) for direct cellular energy metabolism research
Chemical Information:
- Molecular Formula: C₂₁H₂₇N₇O₁₄P₂
- Molecular Weight: ~663.4 g/mol
- Full Name: Nicotinamide Adenine Dinucleotide
- Appearance: White to off-white lyophilized powder
- Solubility: Soluble in sterile water, physiological saline, or buffered solutions (pH 7-8)
- Form: Oxidized NAD⁺ (not NADH) for specific research applications
Research Applications:
NAD+ has been extensively investigated for its critical roles in:
- Cellular Energy Metabolism: Essential cofactor for glycolysis, oxidative phosphorylation, and ATP production
- DNA Repair Mechanisms: Substrate for PARP enzymes in base excision repair pathways
- Longevity Research: Activation of sirtuin proteins (SIRT1-7) linked to lifespan extension
- Aging Studies: Investigation of age-related NAD+ decline and cellular senescence
- Metabolic Disorders: Research on obesity, diabetes, and mitochondrial dysfunction
- Neuroprotection: Studies on neurodegenerative diseases and cognitive decline
- Cardiovascular Health: Endothelial function and vascular repair mechanisms
- Immune Function: Modulation of inflammatory responses and immune cell metabolism
- Oxidative Stress: Cellular antioxidant defense systems and redox balance
Important: This product is strictly for in vitro and research use only. Not intended for human consumption, therapeutic application, or veterinary use.
Mechanism of Action:
NAD+ serves as an essential electron carrier in redox reactions, transferring electrons in metabolic pathways. It acts as a substrate for sirtuins (protein deacetylases) and PARPs (poly-ADP-ribose polymerases), regulating gene expression, DNA repair, and cellular stress responses. Research shows that NAD+ levels decline with age, making it a critical molecule in longevity and age-related disease studies.
Storage & Handling:
- Store lyophilized powder at -20°C (stable for up to 24 months)
- Reconstituted solution: stable for 7-14 days at 2-8°C; for longer storage, freeze at -80°C
- Highly sensitive to light and heat — protect from direct sunlight at all times
- Avoid repeated freeze-thaw cycles to maintain compound integrity
- Use sterile technique for all reconstitution and handling procedures
- Reconstitute in slightly alkaline buffer (pH 7-8) for optimal stability
Safety Disclaimer:
This compound is a research chemical only. It has not been evaluated by the FDA, EMA, or any regulatory authority for safety, efficacy, or pharmacological effects. Researchers must adhere to all institutional and national safety guidelines when handling. The buyer assumes full responsibility for compliance with applicable laws and regulations regarding research compounds. Not for human or veterinary therapeutic use.
Reconstitution Guidelines:
- Reconstitute with sterile water or physiological saline (pH-adjusted if possible)
- Recommended concentration: 10-50 mM depending on research protocol
- Gently swirl vial; avoid vigorous shaking
- Allow powder to fully dissolve (may take 2-3 minutes)
- Store reconstituted solution in sterile, light-protected vial
- Consider adding 1mM DTT for enhanced stability in solution
Note: Certificate of Analysis (CoA) and MSDS available upon request. Bulk quantities available for institutional research groups. Contact support for wholesale pricing or protocol-specific consultations.
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