SS-31 (Elamipretide) 50 MG

145,00 $

Description

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SS-31 (Elamipretide) Research Peptide – Mitochondrial Protection & Cellular Energy

Product Overview:
SS-31, also known as Elamipretide, is a novel mitochondria-targeted synthetic tetrapeptide that has revolutionized research into mitochondrial dysfunction and age-related diseases. This cell-permeable peptide selectively accumulates in mitochondria, where it binds to cardiolipin and stabilizes the mitochondrial inner membrane. SS-31 has been extensively studied for its potential in neurodegenerative diseases, cardiovascular conditions, and metabolic disorders. Our SS-31 is synthesized for advanced mitochondrial and cellular research with pharmaceutical-grade purity.

Key Features:

High Purity: ≥98% purity verified by HPLC-MS analysis
Available Concentration: 10mg lyophilized powder vials
Research Grade: Manufactured in ISO-certified facility under strict quality control
Stable Formulation: Lyophilized powder ensures maximum potency and extended shelf life
Mitochondrial Targeting: Specifically designed for mitochondrial protection research

Chemical Information:

Molecular Formula: C₃₂H₄₉N₉O₅
Molecular Weight: ~639.8 g/mol
Alternative Name: Elamipretide
Structure: D-Arg-2′,6′-dimethyltyrosine-Lys-Phe-NH₂ (alternating D- and L- amino acids)
Appearance: White to off-white lyophilized powder
Solubility: Soluble in sterile water, physiological saline, or bacteriostatic water

Research Applications:

SS-31 has been extensively investigated for its unique mitochondrial protective effects:

Mitochondrial Protection: Stabilizes mitochondrial inner membrane and prevents permeability transition pore opening
Neurodegenerative Diseases: Research in Alzheimer’s, Parkinson’s, ALS, and Huntington’s disease models
Cardiovascular Research: Protection against ischemia-reperfusion injury and heart failure
Metabolic Disorders: Studies on diabetes, obesity, and metabolic syndrome
Aging Research: Investigation into age-related mitochondrial dysfunction and cellular senescence
Muscular Dystrophy: Research on mitochondrial myopathies and muscle wasting diseases
Acute Kidney Injury: Protection against renal ischemia and nephrotoxicity
Oxidative Stress: Reduction of reactive oxygen species (ROS) production in mitochondria

Important: This product is strictly for in vitro and research use only. Not intended for human consumption, therapeutic application, or veterinary use.

Mechanism of Action:

SS-31 selectively accumulates in mitochondria (100-5,000 fold concentration) due to its positive charge and lipophilic properties. It binds specifically to cardiolipin, a unique phospholipid in the mitochondrial inner membrane, preventing its oxidation and stabilizing the membrane structure. This action reduces electron leak from the respiratory chain, decreases ROS production, and prevents opening of the mitochondrial permeability transition pore (mPTP), which is critical for cell survival.

Storage & Handling:

Store lyophilized powder at -20°C (stable for up to 36 months)
Reconstituted solution: stable for 14 days at 2-8°C; for longer storage, freeze at -80°C
Highly sensitive to light and heat — protect from direct sunlight at all times
Avoid repeated freeze-thaw cycles to maintain peptide integrity
Use sterile technique for all reconstitution and handling procedures

Safety Disclaimer:

This peptide is a research chemical only. It has not been evaluated by the FDA, EMA, or any regulatory authority for safety, efficacy, or pharmacological effects. Researchers must adhere to all institutional and national safety guidelines when handling. The buyer assumes full responsibility for compliance with applicable laws and regulations regarding research compounds. Not for human or veterinary therapeutic use.

Reconstitution Guidelines:

Reconstitute with sterile bacteriostatic water or sterile water for injection
Recommended concentration: 1-5 mg/mL depending on research protocol
Gently swirl vial; avoid vigorous shaking to prevent denaturation
Allow powder to fully dissolve (may take 1-2 minutes)
Store reconstituted solution in sterile, light-protected vial

Note: Certificate of Analysis (CoA) available upon request. Bulk quantities available for institutional research groups. Contact support for wholesale pricing or protocol-specific consultations.

What Are Peptides Used For?

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What Are Peptides Used For? A Comprehensive Guide

Peptides are short chains of amino acids that serve as fundamental building blocks of proteins and play crucial roles in numerous biological processes. Due to their small size and high specificity, peptides have become invaluable tools across multiple industries, from medical research to skincare and athletic performance. This article explores the primary applications of peptides and their growing importance in modern science.

1. Medical and Pharmaceutical Research

Peptides are extensively used in drug development and therapeutic applications due to their ability to mimic natural biological processes. Key areas include:

Cancer Treatment: Certain peptides can target tumor cells specifically, delivering chemotherapy drugs directly to malignant tissues while sparing healthy cells.
Hormone Therapy: Synthetic peptides like insulin, growth hormone-releasing peptides, and GLP-1 agonists are used to manage diabetes, growth deficiencies, and metabolic disorders.
Antimicrobial Agents: Antimicrobial peptides (AMPs) fight bacteria, viruses, and fungi, offering alternatives to traditional antibiotics.
Immune Modulation: Peptides help regulate immune responses, showing promise in treating autoimmune diseases and enhancing vaccine efficacy.

2. Anti-Aging and Skincare

In dermatology and cosmetics, peptides are prized for their skin-repairing and rejuvenating properties:

Collagen Stimulation: Signal peptides like Matrixyl and copper peptides boost collagen production, reducing wrinkles and improving skin elasticity.
Skin Barrier Repair: Peptides strengthen the skin's protective barrier, helping retain moisture and resist environmental damage.
Muscle Relaxation: Neurotransmitter-inhibiting peptides (e.g., Argireline) mimic Botox effects, smoothing expression lines.
Wound Healing: Certain peptides accelerate tissue repair, making them valuable in post-procedure skincare.

3. Sports Performance and Recovery

Athletes and fitness enthusiasts use peptides to enhance performance, recovery, and muscle growth:

Muscle Building: Growth hormone secretagogues (GHS) stimulate natural GH release, promoting lean muscle mass.
Fat Loss: Peptides like AOD-9604 target adipose tissue, aiding in weight management without affecting blood sugar.
Injury Recovery: BPC-157 and TB-500 accelerate healing of tendons, ligaments, and muscles.
Endurance Enhancement: Some peptides improve oxygen utilization and cardiovascular efficiency.

Important: Many performance-enhancing peptides are prohibited in competitive sports and should only be used under medical supervision.

4. Scientific Research and Diagnostics

Peptides serve as essential tools in laboratory research and diagnostic applications:

Biomarkers: Specific peptide sequences indicate disease presence, enabling early detection through blood tests.
Drug Delivery: Cell-penetrating peptides (CPPs) transport therapeutic molecules across cell membranes.
Protein Studies: Synthetic peptides help researchers study protein structures and interactions.
Vaccine Development: Peptide-based vaccines stimulate targeted immune responses with fewer side effects.

5. Veterinary Medicine

In veterinary practice, peptides are used for:

Promoting growth and development in livestock
Treating metabolic disorders in animals
Enhancing immune function and disease resistance
Accelerating wound healing in companion animals

Advantages of Peptide-Based Solutions

High Specificity: Peptides target precise receptors with minimal off-target effects.
Low Toxicity: Generally well-tolerated and metabolized safely by the body.
Versatility: Can be designed for countless therapeutic and cosmetic purposes.
Rapid Action: Many peptides work quickly due to small molecular size.

Conclusion

From revolutionary cancer therapies to next-generation skincare and athletic recovery, peptides represent one of the most versatile and promising areas of modern biochemistry. As research advances, we can expect even more innovative applications that harness the power of these remarkable molecules. Whether in medicine, cosmetics, or scientific discovery, peptides continue to shape the future of health and wellness.

Disclaimer: This information is for educational purposes only. Always consult qualified healthcare professionals before using any peptide-based products.