KPV 10MG

Name: KPV 10MG
SKU: 16274
Availability: InStock

55,00 $

Description

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KPV (Lysine-Proline-Valine) Research Peptide – Anti-Inflammatory & Skin Health

Product Overview:
KPV is a synthetic tripeptide derived from the C-terminus of alpha-melanocyte-stimulating hormone (α-MSH). This potent anti-inflammatory peptide has gained significant attention in research for its ability to modulate immune responses, reduce inflammation, and promote tissue healing without the pigmentation effects of full-length MSH. KPV is particularly valuable for studying inflammatory bowel disease, skin conditions, and systemic inflammation. Our KPV is synthesized for advanced biochemical and immunological research with pharmaceutical-grade purity.

Key Features:

High Purity: ≥99% purity verified by HPLC-MS analysis
Available Concentration: 10mg lyophilized powder vials
Research Grade: Manufactured in ISO-certified facility under strict quality control
Stable Formulation: Lyophilized powder ensures maximum potency and extended shelf life
Tripeptide Structure: Minimalist design for targeted anti-inflammatory research

Chemical Information:

Molecular Formula: C₁₆H₃₀N₄O₄
Molecular Weight: ~342.4 g/mol
Sequence: Lysine-Proline-Valine (Lys-Pro-Val)
Appearance: White to off-white lyophilized powder
Solubility: Highly soluble in sterile water, physiological saline, or bacteriostatic water
Derivation: C-terminal fragment of α-MSH (residues 11-13)

Research Applications:

KPV has been investigated in numerous studies for its potential therapeutic effects:

Anti-Inflammatory Mechanisms: Potent modulation of NF-κB pathway and pro-inflammatory cytokines (TNF-α, IL-6, IL-1β)
Inflammatory Bowel Disease (IBD): Research on colitis, Crohn’s disease, and intestinal barrier protection
Skin Inflammation: Studies on dermatitis, psoriasis, eczema, and wound healing
Systemic Inflammation: Investigation of chronic inflammatory conditions and immune dysregulation
Allergy Research: Modulation of mast cell activation and histamine release
Gut Permeability: Research on intestinal tight junction integrity and “leaky gut”
Antimicrobial Effects: Studies on bacterial defense mechanisms in epithelial tissues
Tissue Repair: Promotion of cellular regeneration without fibrosis

Important: This product is strictly for in vitro and research use only. Not intended for human consumption, therapeutic application, or veterinary use.

Mechanism of Action:

KPV acts as a potent anti-inflammatory agent by inhibiting NF-κB nuclear translocation, the master regulator of inflammatory gene expression. It downregulates pro-inflammatory cytokines while preserving immune function. Unlike full-length α-MSH, KPV lacks melanotropic activity, making it ideal for studying pure anti-inflammatory effects without pigmentation side effects. Its small size allows for excellent tissue penetration, particularly in the gastrointestinal tract.

Storage & Handling:

Store lyophilized powder at -20°C (stable for up to 36 months)
Reconstituted solution: stable for 14 days at 2-8°C; for longer storage, freeze at -80°C
Protect from light and moisture at all times
Avoid repeated freeze-thaw cycles to maintain peptide integrity
Use sterile technique for all reconstitution and handling procedures

Safety Disclaimer:

This peptide is a research chemical only. It has not been evaluated by the FDA, EMA, or any regulatory authority for safety, efficacy, or pharmacological effects. Researchers must adhere to all institutional and national safety guidelines when handling. The buyer assumes full responsibility for compliance with applicable laws and regulations regarding research compounds. Not for human or veterinary therapeutic use.

Reconstitution Guidelines:

Reconstitute with sterile bacteriostatic water or sterile water for injection
Recommended concentration: 1-5 mg/mL depending on research protocol
Gently swirl vial; avoid vigorous shaking to prevent denaturation
Allow powder to fully dissolve (may take 1-2 minutes)
Store reconstituted solution in sterile, sealed vial

Note: Certificate of Analysis (CoA) available upon request. Bulk quantities available for institutional research groups. Contact support for wholesale pricing or protocol-specific consultations.

What Are Peptides Used For?

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What Are Peptides Used For? A Comprehensive Guide

Peptides are short chains of amino acids that serve as fundamental building blocks of proteins and play crucial roles in numerous biological processes. Due to their small size and high specificity, peptides have become invaluable tools across multiple industries, from medical research to skincare and athletic performance. This article explores the primary applications of peptides and their growing importance in modern science.

1. Medical and Pharmaceutical Research

Peptides are extensively used in drug development and therapeutic applications due to their ability to mimic natural biological processes. Key areas include:

Cancer Treatment: Certain peptides can target tumor cells specifically, delivering chemotherapy drugs directly to malignant tissues while sparing healthy cells.
Hormone Therapy: Synthetic peptides like insulin, growth hormone-releasing peptides, and GLP-1 agonists are used to manage diabetes, growth deficiencies, and metabolic disorders.
Antimicrobial Agents: Antimicrobial peptides (AMPs) fight bacteria, viruses, and fungi, offering alternatives to traditional antibiotics.
Immune Modulation: Peptides help regulate immune responses, showing promise in treating autoimmune diseases and enhancing vaccine efficacy.

2. Anti-Aging and Skincare

In dermatology and cosmetics, peptides are prized for their skin-repairing and rejuvenating properties:

Collagen Stimulation: Signal peptides like Matrixyl and copper peptides boost collagen production, reducing wrinkles and improving skin elasticity.
Skin Barrier Repair: Peptides strengthen the skin's protective barrier, helping retain moisture and resist environmental damage.
Muscle Relaxation: Neurotransmitter-inhibiting peptides (e.g., Argireline) mimic Botox effects, smoothing expression lines.
Wound Healing: Certain peptides accelerate tissue repair, making them valuable in post-procedure skincare.

3. Sports Performance and Recovery

Athletes and fitness enthusiasts use peptides to enhance performance, recovery, and muscle growth:

Muscle Building: Growth hormone secretagogues (GHS) stimulate natural GH release, promoting lean muscle mass.
Fat Loss: Peptides like AOD-9604 target adipose tissue, aiding in weight management without affecting blood sugar.
Injury Recovery: BPC-157 and TB-500 accelerate healing of tendons, ligaments, and muscles.
Endurance Enhancement: Some peptides improve oxygen utilization and cardiovascular efficiency.

Important: Many performance-enhancing peptides are prohibited in competitive sports and should only be used under medical supervision.

4. Scientific Research and Diagnostics

Peptides serve as essential tools in laboratory research and diagnostic applications:

Biomarkers: Specific peptide sequences indicate disease presence, enabling early detection through blood tests.
Drug Delivery: Cell-penetrating peptides (CPPs) transport therapeutic molecules across cell membranes.
Protein Studies: Synthetic peptides help researchers study protein structures and interactions.
Vaccine Development: Peptide-based vaccines stimulate targeted immune responses with fewer side effects.

5. Veterinary Medicine

In veterinary practice, peptides are used for:

Promoting growth and development in livestock
Treating metabolic disorders in animals
Enhancing immune function and disease resistance
Accelerating wound healing in companion animals

Advantages of Peptide-Based Solutions

High Specificity: Peptides target precise receptors with minimal off-target effects.
Low Toxicity: Generally well-tolerated and metabolized safely by the body.
Versatility: Can be designed for countless therapeutic and cosmetic purposes.
Rapid Action: Many peptides work quickly due to small molecular size.

Conclusion

From revolutionary cancer therapies to next-generation skincare and athletic recovery, peptides represent one of the most versatile and promising areas of modern biochemistry. As research advances, we can expect even more innovative applications that harness the power of these remarkable molecules. Whether in medicine, cosmetics, or scientific discovery, peptides continue to shape the future of health and wellness.

Disclaimer: This information is for educational purposes only. Always consult qualified healthcare professionals before using any peptide-based products.