NAD+ 500MG

Name: NAD+ 500MG
SKU: 16271
Availability: InStock

55,00 $

Description

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NAD+ (Nicotinamide Adenine Dinucleotide) Research Compound – Cellular Energy & Longevity

Product Overview:
NAD+ (Nicotinamide Adenine Dinucleotide) is a crucial coenzyme found in all living cells, playing a fundamental role in energy metabolism, DNA repair, and cellular signaling. This oxidized form of NAD is essential for the function of sirtuins, PARPs, and other enzymes critical for longevity and cellular health. Our NAD+ is synthesized for advanced biochemical and aging research with pharmaceutical-grade purity.

Key Features:

High Purity: ≥99% purity verified by independent HPLC analysis
Available Concentrations: 500mg lyophilized powder vials
Research Grade: Manufactured in ISO-certified facility under strict quality control
Stable Formulation: Lyophilized powder ensures maximum potency and extended shelf life
Biologically Active: Oxidized form (NAD⁺) for direct cellular energy metabolism research

Chemical Information:

Molecular Formula: C₂₁H₂₇N₇O₁₄P₂
Molecular Weight: ~663.4 g/mol
Full Name: Nicotinamide Adenine Dinucleotide
Appearance: White to off-white lyophilized powder
Solubility: Soluble in sterile water, physiological saline, or buffered solutions (pH 7-8)
Form: Oxidized NAD⁺ (not NADH) for specific research applications

Research Applications:

NAD+ has been extensively investigated for its critical roles in:

Cellular Energy Metabolism: Essential cofactor for glycolysis, oxidative phosphorylation, and ATP production
DNA Repair Mechanisms: Substrate for PARP enzymes in base excision repair pathways
Longevity Research: Activation of sirtuin proteins (SIRT1-7) linked to lifespan extension
Aging Studies: Investigation of age-related NAD+ decline and cellular senescence
Metabolic Disorders: Research on obesity, diabetes, and mitochondrial dysfunction
Neuroprotection: Studies on neurodegenerative diseases and cognitive decline
Cardiovascular Health: Endothelial function and vascular repair mechanisms
Immune Function: Modulation of inflammatory responses and immune cell metabolism
Oxidative Stress: Cellular antioxidant defense systems and redox balance

Important: This product is strictly for in vitro and research use only. Not intended for human consumption, therapeutic application, or veterinary use.

Mechanism of Action:

NAD+ serves as an essential electron carrier in redox reactions, transferring electrons in metabolic pathways. It acts as a substrate for sirtuins (protein deacetylases) and PARPs (poly-ADP-ribose polymerases), regulating gene expression, DNA repair, and cellular stress responses. Research shows that NAD+ levels decline with age, making it a critical molecule in longevity and age-related disease studies.

Storage & Handling:

Store lyophilized powder at -20°C (stable for up to 24 months)
Reconstituted solution: stable for 7-14 days at 2-8°C; for longer storage, freeze at -80°C
Highly sensitive to light and heat — protect from direct sunlight at all times
Avoid repeated freeze-thaw cycles to maintain compound integrity
Use sterile technique for all reconstitution and handling procedures
Reconstitute in slightly alkaline buffer (pH 7-8) for optimal stability

Safety Disclaimer:

This compound is a research chemical only. It has not been evaluated by the FDA, EMA, or any regulatory authority for safety, efficacy, or pharmacological effects. Researchers must adhere to all institutional and national safety guidelines when handling. The buyer assumes full responsibility for compliance with applicable laws and regulations regarding research compounds. Not for human or veterinary therapeutic use.

Reconstitution Guidelines:

Reconstitute with sterile water or physiological saline (pH-adjusted if possible)
Recommended concentration: 10-50 mM depending on research protocol
Gently swirl vial; avoid vigorous shaking
Allow powder to fully dissolve (may take 2-3 minutes)
Store reconstituted solution in sterile, light-protected vial
Consider adding 1mM DTT for enhanced stability in solution

Note: Certificate of Analysis (CoA) and MSDS available upon request. Bulk quantities available for institutional research groups. Contact support for wholesale pricing or protocol-specific consultations.

What Are Peptides Used For?

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What Are Peptides Used For? A Comprehensive Guide

Peptides are short chains of amino acids that serve as fundamental building blocks of proteins and play crucial roles in numerous biological processes. Due to their small size and high specificity, peptides have become invaluable tools across multiple industries, from medical research to skincare and athletic performance. This article explores the primary applications of peptides and their growing importance in modern science.

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Disclaimer: This information is for educational purposes only. Always consult qualified healthcare professionals before using any peptide-based products.