Vitamin B12

Name: Vitamin B12
SKU: 16470
Availability: InStock

90,00 $

Description

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Vitamin B12 (Cobalamin) Research Compound – Cellular Energy & Neurological Health

Product Overview:
Vitamin B12, also known as cobalamin, is a crucial water-soluble vitamin essential for DNA synthesis, red blood cell formation, and neurological function. This cobalt-containing compound exists in several forms, with methylcobalamin and cyanocobalamin being the most common in research applications. Vitamin B12 serves as a cofactor for methionine synthase and methylmalonyl-CoA mutase, making it indispensable for cellular metabolism and myelin synthesis. Our Vitamin B12 is synthesized for advanced biochemical and nutritional research with pharmaceutical-grade purity.

Key Features:

High Purity: ≥98% purity verified by independent HPLC analysis
Available Forms: Methylcobalamin and Cyanocobalamin variants
Research Grade: Manufactured in ISO-certified facility under strict quality control
Stable Formulation: Lyophilized powder ensures maximum potency and extended shelf life
Essential Cofactor: Critical for one-carbon metabolism and neurological research

Chemical Information:

Molecular Formula: C₆₃H₈₈CoN₁₄O₁₄P (varies by form)
Molecular Weight: ~1,355.4 g/mol (base cobalamin structure)
Appearance: Dark red crystalline powder (characteristic cobalt complex)
Solubility: Soluble in water, physiological saline, or buffered solutions
- Cyanocobalamin Form: Contains cyanide ligand (stable, common research form)
- Methylcobalamin Form: Contains methyl group (bioactive neurological form)

Research Applications:

Vitamin B12 has been extensively investigated for its critical roles in:

One-Carbon Metabolism: Research on methionine cycle, folate metabolism, and homocysteine regulation
Neurological Health: Studies on myelin synthesis, nerve regeneration, and cognitive function
Hematological Research: Investigation of red blood cell formation and pernicious anemia models
DNA Synthesis: Research on cellular replication and genomic stability
Mitochondrial Function: Studies on energy metabolism and methylmalonic acid metabolism
Cardiovascular Health: Research on homocysteine-related vascular disease
Aging Studies: Investigation of age-related B12 deficiency and cognitive decline
Nutritional Biochemistry: Malabsorption syndromes and deficiency mechanisms

Important: This product is strictly for in vitro and research use only. Not intended for human consumption, therapeutic application, or veterinary use.

Mechanism of Action:

Vitamin B12 serves as an essential cofactor for two critical enzymes: methionine synthase (required for methionine production and DNA methylation) and methylmalonyl-CoA mutase (required for odd-chain fatty acid and amino acid metabolism). Deficiency leads to impaired DNA synthesis, megaloblastic anemia, and neurological damage through disrupted myelin maintenance. Its complex cobalt-corrin ring structure allows for unique redox chemistry in these enzymatic reactions.

Storage & Handling:

Store lyophilized powder at -20°C (stable for up to 36 months)
Reconstituted solution: stable for 14 days at 2-8°C; for longer storage, freeze at -80°C
Protect from light at all times — photolabile compound
Avoid repeated freeze-thaw cycles to maintain compound integrity
Use sterile technique for all reconstitution and handling procedures
Store in amber vials to protect from photo-degradation

Safety Disclaimer:

This compound is a research chemical only. It has not been evaluated by the FDA, EMA, or any regulatory authority for safety, efficacy, or pharmacological effects. Researchers must adhere to all institutional and national safety guidelines when handling. The buyer assumes full responsibility for compliance with applicable laws and regulations regarding research compounds. Not for human or veterinary therapeutic use.

Reconstitution Guidelines:

Reconstitute with sterile water for injection or physiological saline
Recommended concentration: 1-10 mg/mL depending on research protocol
Gently swirl vial; avoid vigorous shaking
Allow powder to fully dissolve (may take 2-3 minutes)
Store reconstituted solution in sterile, light-protected vial
Working solutions should be prepared fresh when possible

Note: Certificate of Analysis (CoA) and MSDS available upon request. Bulk quantities available for institutional research groups. Contact support for wholesale pricing or protocol-specific consultations.

What Are Peptides Used For?

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What Are Peptides Used For? A Comprehensive Guide

Peptides are short chains of amino acids that serve as fundamental building blocks of proteins and play crucial roles in numerous biological processes. Due to their small size and high specificity, peptides have become invaluable tools across multiple industries, from medical research to skincare and athletic performance. This article explores the primary applications of peptides and their growing importance in modern science.

1. Medical and Pharmaceutical Research

Peptides are extensively used in drug development and therapeutic applications due to their ability to mimic natural biological processes. Key areas include:

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Hormone Therapy: Synthetic peptides like insulin, growth hormone-releasing peptides, and GLP-1 agonists are used to manage diabetes, growth deficiencies, and metabolic disorders.
Antimicrobial Agents: Antimicrobial peptides (AMPs) fight bacteria, viruses, and fungi, offering alternatives to traditional antibiotics.
Immune Modulation: Peptides help regulate immune responses, showing promise in treating autoimmune diseases and enhancing vaccine efficacy.

2. Anti-Aging and Skincare

In dermatology and cosmetics, peptides are prized for their skin-repairing and rejuvenating properties:

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Wound Healing: Certain peptides accelerate tissue repair, making them valuable in post-procedure skincare.

3. Sports Performance and Recovery

Athletes and fitness enthusiasts use peptides to enhance performance, recovery, and muscle growth:

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Endurance Enhancement: Some peptides improve oxygen utilization and cardiovascular efficiency.

Important: Many performance-enhancing peptides are prohibited in competitive sports and should only be used under medical supervision.

4. Scientific Research and Diagnostics

Peptides serve as essential tools in laboratory research and diagnostic applications:

Biomarkers: Specific peptide sequences indicate disease presence, enabling early detection through blood tests.
Drug Delivery: Cell-penetrating peptides (CPPs) transport therapeutic molecules across cell membranes.
Protein Studies: Synthetic peptides help researchers study protein structures and interactions.
Vaccine Development: Peptide-based vaccines stimulate targeted immune responses with fewer side effects.

5. Veterinary Medicine

In veterinary practice, peptides are used for:

Promoting growth and development in livestock
Treating metabolic disorders in animals
Enhancing immune function and disease resistance
Accelerating wound healing in companion animals

Advantages of Peptide-Based Solutions

High Specificity: Peptides target precise receptors with minimal off-target effects.
Low Toxicity: Generally well-tolerated and metabolized safely by the body.
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Conclusion

From revolutionary cancer therapies to next-generation skincare and athletic recovery, peptides represent one of the most versatile and promising areas of modern biochemistry. As research advances, we can expect even more innovative applications that harness the power of these remarkable molecules. Whether in medicine, cosmetics, or scientific discovery, peptides continue to shape the future of health and wellness.

Disclaimer: This information is for educational purposes only. Always consult qualified healthcare professionals before using any peptide-based products.